BDBM50326395 (2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl}pyrrolidine-2-boronic Acid::CHEMBL1243184

SMILES OB(O)[C@@H]1CCCN1C(=O)[C@@H]1C[C@@H](CC(=O)N2Cc3ccccc3C2)C(=O)N1

InChI Key InChIKey=ITLZQNVDXDVBBF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326395   

TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326395((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant FAP expressed in Hi5 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326395((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant His-tagged DPP2 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326395((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant His-tagged DPP8 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326395((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant His-tagged DPP9 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326395((2R)-1-{(2S, 4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2...)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant His-tagged DPP4 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed