BDBM50346238 (5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)(thiophen-2-yl)methanone::CHEMBL1782188

SMILES Oc1ccccc1C1CC(=NN1C(=O)c1cccs1)c1cccnc1

InChI Key InChIKey=FZEFXBSMKLLKED-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50346238   

TargetRAC-beta serine/threonine-protein kinase(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346238((5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed