BDBM50355101 CHEMBL1835324

SMILES CC(C)[C@H](NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCc2ccccc2[C@H]1C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=CALHLXBTFCJYKI-UKQFZSMWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355101   

TargetCaspase-2(Human)
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355101(CHEMBL1835324)
Affinity DataIC50:  2.26E+3nMAssay Description:Inhibition of human Myc-DDK tagged caspase-2 expressed in HEK293 T17 cells using Ac-VDVAD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCaspase-2(Human)
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355101(CHEMBL1835324)
Affinity DataIC50:  22nMAssay Description:Inhibition of caspase-2 (amino acids 170 to 452) using Ac-VDVAD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCaspase-3(Human)
Chdi Management

Curated by ChEMBL
LigandPNGBDBM50355101(CHEMBL1835324)
Affinity DataIC50:  233nMAssay Description:Inhibition of C-terminal histidine-tagged caspase-3 using Ac-DEVD-AMC coumarin-120 as substrate after 20 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed