BDBM50355489 CHEMBL1835867

SMILES CN1CCC(CC1)c1ccc(Nc2nc(N)n(n2)-c2ccccn2)cc1

InChI Key InChIKey=JBBBYMPMAJVCSI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355489   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355489(CHEMBL1835867)
Affinity DataKi:  2nMAssay Description:Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355489(CHEMBL1835867)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355489(CHEMBL1835867)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed