BDBM50355961 CHEMBL1910893

SMILES Oc1ccc(-c2ccc3c(-c4ccc(N5CCNCC5)cc4)n[nH]c3n2)cc1

InChI Key InChIKey=DGLXOJMLPNCUDE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50355961   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355961BDBM50355961(CHEMBL1910893)
Affinity DataIC50: 4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355961BDBM50355961(CHEMBL1910893)
Affinity DataIC50: 7nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355961BDBM50355961(CHEMBL1910893)
Affinity DataIC50: 9nMAssay Description:Inhibition of PIM1 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355961BDBM50355961(CHEMBL1910893)
Affinity DataIC50: 12nMAssay Description:Inhibition of PIM3 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355961BDBM50355961(CHEMBL1910893)
Affinity DataIC50: 18nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355961BDBM50355961(CHEMBL1910893)
Affinity DataIC50: 39nMAssay Description:Inhibition of PIM2 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed