BDBM50355962 CHEMBL1910892

SMILES Oc1ccc(-c2ccc3c(-c4ccc(N5CCNCC5)cc4)c[nH]c3n2)cc1

InChI Key InChIKey=VFFKOUSSVDBQAF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50355962   

TargetSerine/threonine-protein kinase pim-1(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355962BDBM50355962(CHEMBL1910892)
Affinity DataIC50: 30nMAssay Description:Inhibition of PIM1 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355962BDBM50355962(CHEMBL1910892)
Affinity DataIC50: 58nMAssay Description:Inhibition of PIM3 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355962BDBM50355962(CHEMBL1910892)
Affinity DataIC50: 111nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355962BDBM50355962(CHEMBL1910892)
Affinity DataIC50: 283nMAssay Description:Inhibition of PIM2 using BAD peptide as substrate preincubated for 15 mins measured after 60 to 100 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355962BDBM50355962(CHEMBL1910892)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355962BDBM50355962(CHEMBL1910892)
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed