BDBM50400602 CHEMBL2206278
SMILES CCN1C(C)(C)CC(CC1(C)C)Oc1ccc(nc1)C(=O)Nc1ccc(NC(=O)Nc2cc(on2)C(C)(C)C)cc1
InChI Key InChIKey=JVCWPUFNLFSKFS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50400602 Sort by
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to PDGFRbeta expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Binding affinity to PDGFRalpha expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of KIT phosphorylation in human H526 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to KIT expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 phosphorylation in human MV4-11 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10.5nMAssay Description:Inhibition of M-CSF-induced FK506 -fussed CSF1R phosphorylation expressed in HEK293 cells after 2 hrs by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 46.3nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.57nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKd: 0.5nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 7.70nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human MG63 cellsMore data for this Ligand-Target Pair