BDBM50420192 CHEMBL2074851

SMILES CC[n+]1c(CC2C=C(C)N=C(N2C)c2ccccc2)ccc2ccccc12

InChI Key InChIKey=WNJQWMVHCPGIAR-UHFFFAOYSA-N

Data  4 KI  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50420192   

TargetSolute carrier family 22 member 1(Rat)
Bayerische Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataKi:  130nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Human)
Anatomisches Institut Der Bayerischen Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataKi:  210nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Bayerische Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 400nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Bayerische Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 450nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Bayerische Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 510nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Bayerische Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataKi:  670nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataKi:  861nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (apical to cell) in OCT2-expressing NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.20E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 3(Human)
Universidade Do Porto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.76E+3nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.2 uM) in OCT3-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 2.56E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake (TEA: 10 uM) in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 1.50E+4nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Bayerische Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 8.90E+4nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 1(Rat)
Bayerische Julius-Maximilians-Universit£T

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 2.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed
TargetSolute carrier family 22 member 2(Rat)
University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50420192BDBM50420192(CHEMBL2074851)
Affinity DataIC50: 2.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of Amantadine uptake (in the presence of bicarbonate) (Amantadine: 10 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMed