BDBM50436053 CHEMBL2396992
SMILES Cc1[nH]c2cc(Cl)cc(Cl)c2c1CCN
InChI Key InChIKey=JCTJISIFGZHOFY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50436053
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of KRas (unknown origin) by nucleotide release assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of SOS-mediated nucleotide release activityMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+6nMAssay Description:Binding affinity to KRAS (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+4nMAssay Description:Inhibition of KRas activation in HEK 293T-REx Flp-In cells harboring Venus-RBD-CRD/mCherry-CAAX assessed as reduction in Venus-RBD-CRD recruitment to...More data for this Ligand-Target Pair
Affinity DataIC50: 3.42E+5nMAssay Description:Inhibition of full-length human KRas4B (amino acids 1 to 188)-SOS interaction assessed as inhibition of nucleotide exchange activityMore data for this Ligand-Target Pair