BDBM50490889 CHEMBL2347723
SMILES COc1ccccc1-c1ccc2nc(NC(=O)NCCO)sc2c1
InChI Key InChIKey=LAAHHHDILCOULN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50490889
TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)
Curated by ChEMBL
Korea Institute of Science and Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Mouse)
"G. D'Annunzio" University of Chieti-Pescara
Curated by ChEMBL
"G. D'Annunzio" University of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of Abl T315I mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Mouse)
"G. D'Annunzio" University of Chieti-Pescara
Curated by ChEMBL
"G. D'Annunzio" University of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of wild type Abl in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
Korea Institute of Science and Technology (Kaist)
Curated by ChEMBL
Korea Institute of Science and Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair