BDBM50490889 CHEMBL2347723

SMILES COc1ccccc1-c1ccc2nc(NC(=O)NCCO)sc2c1

InChI Key InChIKey=LAAHHHDILCOULN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50490889   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490889(CHEMBL2347723)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)TBA
LigandPNGBDBM50490889(CHEMBL2347723)
Affinity DataIC50:  140nMAssay Description:Inhibition of Abl T315I mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase ABL1(Mus musculus)TBA
LigandPNGBDBM50490889(CHEMBL2347723)
Affinity DataIC50:  89nMAssay Description:Inhibition of wild type Abl in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490889(CHEMBL2347723)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails PubMed