BDBM50495090 CHEMBL3102903

SMILES CCCCCCCCOc1ccc(cc1C(F)(F)F)-c1cnc(s1)[C@@](C)(N)COP(O)(O)=O

InChI Key InChIKey=JYIWELIWYZVXHB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50495090   

TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50:  0.440nMAssay Description:Agonist activity at human S1P1R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human S1P5R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human S1P4R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50495090(CHEMBL3102903)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human S1P3R expressed in HEK293T cells assessed as [35S]GTPgammaS binding after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed