BDBM50513317 CHEMBL4465620
SMILES O=C(NCC(=S)NCCCC[C@@H]1NC(=O)CNC1=O)c1ccccc1Nc1cccc(OCCc2ccccc2)c1
InChI Key InChIKey=MTBMBXFNDPBHBW-MHZLTWQESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50513317
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.92E+4nMAssay Description:Inhibition of human N-terminal His-tagged SIRT3 (102 to 399 residues) expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 resid...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.74E+4nMAssay Description:Inhibition of human N-terminal His-tagged SIRT1 expressed in Escherichia coli using p53 (Arg-His-Lys-Lys(Ac)) (379 to 382 residues) as substrate incu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair