BDBM50530216 CHEMBL4582201
SMILES [H][C@@]12CC[C@@]([H])(C1)[C@H]([C@@H]2N)c1ccc(Cl)nc1
InChI Key InChIKey=NKHNTAYDCXZLFL-IZLWQMGWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50530216
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7* nAChR in rat brain P2 membranes after 2.5 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7* nAChR in rat brain P2 membranes after 2.5 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonist activity at human alpha7 nAChR expressed in mouse Neuro2a cells co-expressing chaperone NACHO assessed as increase in intracellular Ca2+ leve...More data for this Ligand-Target Pair
Affinity DataEC50: 2.71E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataEC50: 430nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.71E+3nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Agonist activity at human alpha7 nAChR expressed in mouse Neuro2a cells co-expressing chaperone NACHO assessed as increase in intracellular Ca2+ leve...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
University of Florence
Curated by ChEMBL
University of Florence
Curated by ChEMBL
Affinity DataEC50: 430nMAssay Description:Agonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes after 4 to 5 days at -60 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair