BDBM50539195 CHEMBL4647379

SMILES Cc1cc(C)c(-c2c(C)nn(C)c2C)cc1NC(=O)c1ccc(OCc2ccccn2)cc1

InChI Key InChIKey=VVBNZUFJZAESEF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539195   

TargetSmoothened homolog(Mouse)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50539195BDBM50539195(CHEMBL4647379)
Affinity DataEC50:  3.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed