BDBM50539195 CHEMBL4647379

SMILES Cc1nn(C)c(C)c1-c1cc(NC(=O)c2ccc(OCc3ccccn3)cc2)c(C)cc1C

InChI Key InChIKey=VVBNZUFJZAESEF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539195   

TargetSmoothened homolog(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539195(CHEMBL4647379)
Affinity DataEC50:  3.10nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed