BDBM50572102 CHEMBL4871511

SMILES CN1CC(COc2ccn3c(cnc3c2)-c2cc(NCc3ccc(cc3)-c3cnn(C)c3)ncn2)C1

InChI Key InChIKey=DYMGRNVMAGSZDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50572102   

TargetMast/stem cell growth factor receptor Kit(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50572102(CHEMBL4871511)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant C-KIT V654A mutant (544 to end residues) using GGMEDIYEFMGGKKK as substrate measured after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50572102(CHEMBL4871511)
Affinity DataIC50: 61nMAssay Description:Inhibition of KIT (delta 560 to 576 residues) deletion/V654A double mutant autophosphorylation at Y703 in human GIST-430/654 harboring KIT (delta560 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed