BDBM50572104 CHEMBL4852385

SMILES COCCN1CCC(COc2ccn3c(cnc3c2)-c2cc(NCc3ccc(cc3)-c3cnn(C)n3)ncn2)CC1

InChI Key InChIKey=PWVLANQLSSFMPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50572104   

TargetMast/stem cell growth factor receptor Kit(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50572104(CHEMBL4852385)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant C-KIT V654A mutant (544 to end residues) using GGMEDIYEFMGGKKK as substrate measured after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed