BDBM50572107 CHEMBL4853236

SMILES CNC1CN(C1)c1ccn2c(cnc2c1)-c1cc(NCc2ccc(cc2)-c2cnn(C)c2)ncn1

InChI Key InChIKey=JARCJAZGKKSDOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50572107   

TargetMast/stem cell growth factor receptor Kit(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50572107(CHEMBL4853236)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant C-KIT V654A mutant (544 to end residues) using GGMEDIYEFMGGKKK as substrate measured after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed