BDBM50578692 CHEMBL4877950

SMILES COc1ccc(CNC(=O)C(=O)[C@@H]2CCCN2C(=O)CNC(=O)c2ccnc3ccccc23)cc1OC

InChI Key InChIKey=QYNUSKJDVJHHFJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50578692   

TargetAcyl-protein thioesterase 1(Rat)
The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578692BDBM50578692(CHEMBL4877950)
Affinity DataIC50: 0.0890nMAssay Description:Inhibition of SF-tagged FAP (unknown origin) expressed in Drosophila S2 cells using fluorogenic substrate by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578692BDBM50578692(CHEMBL4877950)
Affinity DataKi:  0.190nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells immobilized on plate surface using specific antibody assessed as inhibition constant meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetProlyl endopeptidase FAP(Human)
Charles University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578692BDBM50578692(CHEMBL4877950)
Affinity DataIC50: 0.230nMAssay Description:Inhibition of recombinant human FAP extracted from S2 cells using fluorogenic FAP as specific substrate measured after 10 mins incubation by 7-amino-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578692BDBM50578692(CHEMBL4877950)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SF-tagged DPP4 (unknown origin) expressed in Drosophila S2 cells using fluorogenic substrate by spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed