BDBM50588232 CHEMBL5180399

SMILES N[C@@H]1CCCC12CCN(c1nc3[nH]nc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]1)CC2

InChI Key InChIKey=OSIQJCVMJNUAPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50588232   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
University of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50588232BDBM50588232(CHEMBL5180399)
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal his6-tagged wild type recombinant human SHP2 (1 to 597 residues) expressed in Escherichia coli BL21 (DE3) cells using fluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed