BDBM50593495 CHEMBL5196156
SMILES [H][C@]12CC[C@]([H])(CN(C1)c1nc(C)ns1)C2NC1=NC2C=CC=C(C2=N1)c1ccc(F)c(F)c1F
InChI Key InChIKey=VOROBJLBTJUGCC-GKMUEVJASA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50593495
Affinity DataIC50: 1nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as decrease in free Abeta42 levelsMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Indian Institute of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Modulation of gamma-secretase (unknown origin) assessed as decrease in total Abeta42 levelsMore data for this Ligand-Target Pair