BDBM50595739 CHEMBL5178416

SMILES COc1ccc2[nH]c(=O)c(cc2c1)C(N1CCN(CC1)C1CCCCC1)c1nnnn1CCc1ccccc1

InChI Key InChIKey=ZVWPOIUAPXDLMB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595739   

TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  0.260nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  1nMAssay Description:Activation of human EAAT2 expressed in rat Astrocytes assessed as glutamate uptake by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  0.260nMAssay Description:Activation of human EAAT2 expressed in COS cells assessed as glutamate uptakeMore data for this Ligand-Target Pair
In DepthDetails PubMed