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Found 3 Enz. Inhib. hit(s) with Target = 'Excitatory amino acid transporter 2' and Ligand = 'BDBM50595739'
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  0.260nMAssay Description:Activation of human EAAT2 overexpressed in MDCK cells assessed as glutamate reuptake incubated for 5 mins by LCMS assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  1nMAssay Description:Activation of human EAAT2 expressed in rat Astrocytes assessed as glutamate uptake by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Drexel University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50595739(CHEMBL5178416)
Affinity DataEC50:  0.260nMAssay Description:Activation of human EAAT2 expressed in COS cells assessed as glutamate uptakeMore data for this Ligand-Target Pair
In DepthDetails PubMed