BDBM50599167 CHEMBL5195228

SMILES CCN(CC)Cc1ccccc1CNC(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1

InChI Key InChIKey=VINBNLJQGNXIFH-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50599167   

TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599167(CHEMBL5195228)
Affinity DataKi:  0.610nMAssay Description:Inhibition of human BChE assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599167(CHEMBL5195228)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to human BChE assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599167(CHEMBL5195228)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of horse serum BChE using acetylthiocholine iodide or butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetCholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50599167(CHEMBL5195228)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human BChE using acetylthiocholine iodide or butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed