BDBM50605060 CHEMBL5198290::US11891386, Compound 004
SMILES CNC(=O)c1csc(n1)C(=O)c1c[nH]c2ccccc12
InChI Key InChIKey=GOVAEEIQDCTMOG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50605060
Affinity DataKi: 88nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Binding affinity to AhR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Agonist activity at human PXR transfected in human LS180 cells cotransfected with luciferase reporter plasmid p2A4-Luc assessed as transcriptional ac...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 231nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.21E+4nMAssay Description:Displacement of fluorescence labeled ligand from human PXR ligand binding domain by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair