BDBM50616135 CHEMBL5405832

SMILES COc1ccc2CN(Cc2c1Nc1cccc(c1)C(F)(F)F)C#N

InChI Key InChIKey=GCTSHJXOIFKTDC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50616135   

TargetTranscriptional enhancer factor TEF-3(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50616135(CHEMBL5405832)
Affinity DataIC50: 200nMAssay Description:Displacement of FAM- labeled YAP1 peptide (60 to 99 residues) from human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21 (DE3) cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50616135(CHEMBL5405832)
Affinity DataIC50: 300nMAssay Description:Displacement of FAM- labeled YAP1 peptide (60 to 99 residues) from human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21 (DE3) cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50616135(CHEMBL5405832)
Affinity DataIC50: 300nMAssay Description:Inhibition of TEAD4 (unknown origin) transfected in human HEK293 cells co-transfected with renilla plasmid assessed as inhibition of transcriptional ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-4(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50616135(CHEMBL5405832)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of FAM- labeled YAP1 peptide (60 to 99 residues) from human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21 (DE3) cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed