BDBM50629976 CHEMBL5409470

SMILES c1ccc(cc1)Oc2cccc(c2)CCc3cn4c(n3)[C@@H]([C@H]([C@@H]([C@H]4C(=O)O)O)O)O

InChI Key InChIKey=FCQUVPLCJSCNPK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50629976   

TargetBeta-glucuronidase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629976(CHEMBL5409470)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human GUSbeta using 4-MUG as substrate pre-incubated for 10 mins followed by substrate addition and measured after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetHeparanase(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50629976(CHEMBL5409470)
Affinity DataIC50: 467nMAssay Description:Inhibition of recombinant human HPSE1 using biotinylated heparan sulfate-Eu cryptate as substrate pre-incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)