BDBM50637394 CHEMBL5564780

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn(CCCCC4CN(CCCCC(=O)Nc5cccc6c5CN(C5CCC(=O)NC5=O)C6=O)N=N4)c4ncnc(N)c34)cc2)no1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50637394   

TargetReceptor-type tyrosine-protein kinase FLT3(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50637394(CHEMBL5564780)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of FLT3 ITD mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50637394(CHEMBL5564780)
Affinity DataIC50: 36nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50637394(CHEMBL5564780)
Affinity DataIC50: 116nMAssay Description:Inhibition of FLT3 ITD/F691L mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50637394(CHEMBL5564780)
Affinity DataIC50: 121nMAssay Description:Inhibition of FLT3 ITD/D835V mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50637394(CHEMBL5564780)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed