BDBM50637674 CHEMBL5557958

SMILES Cc1nc2ccc(-c3ccncc3)nn2c1-c1cccc(OC(F)(F)F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50637674   

LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataKd:  0.0100nMAssay Description:Binding affinity to biotinylated N-terminal TEV-fused/hexahistidine tagged C-terminal avidin tagged human DYRK1A kinase domain (127 to 485 residues) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataKd:  18nMAssay Description:Binding affinity to biotinylated super-streptavidin biosensor immobilised CLK2 (unknown origin) assessed as dissociation constant by biolayer interfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataKd:  20nMAssay Description:Binding affinity to biotinylated super-streptavidin biosensor immobilised DYRK1A (unknown origin) assessed as dissociation constant by biolayer inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataIC50: 28nMAssay Description:Displacement of kinase tracer 236 from ATP-binding site of biotinylated N-terminal TEV-fused/hexahistidine tagged C-terminal avidin tagged human DYRK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataKd:  31nMAssay Description:Binding affinity to biotinylated N-terminal TEV-fused/hexahistidine tagged C-terminal avidin tagged human DYRK1A kinase domain (127 to 485 residues) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataKd:  39nMAssay Description:Binding affinity to biotinylated super-streptavidin biosensor immobilised Haspin (unknown origin) assessed as dissociation constant by biolayer inter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50637674(CHEMBL5557958)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to biotinylated super-streptavidin biosensor immobilised CLK1 (unknown origin) assessed as dissociation constant by biolayer interfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed