BDBM50641568 CHEMBL5572459

SMILES CC1=CC[C@@H]2C[C@H]1[C@H](c1ccnc3ccccc13)NC2(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50641568   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641568(CHEMBL5572459)
Affinity DataEC50:  550nMAssay Description:Noncompetitive inhibition of epibatidine-induced receptor activation at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as reduction in calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641568(CHEMBL5572459)
Affinity DataIC50: 920nMAssay Description:Inhibition of epibatidine-induced receptor activation at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as reduction in calcium flux preinc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641568(CHEMBL5572459)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-epibatidine from alpha2C receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641568(CHEMBL5572459)
Affinity DataIC50: 1.47E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-2A adrenergic receptor(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641568(CHEMBL5572459)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]-epibatidine from alpha2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641568(CHEMBL5572459)
Affinity DataIC50: 1.09E+4nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Illinois Chicago

Curated by ChEMBL
LigandPNGBDBM50641568(CHEMBL5572459)
Affinity DataIC50: 1.16E+5nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells assessed as inhibition of nicotine induced calcium flux preincubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed