BDBM50650863 CHEMBL5632719

SMILES O=C(Nc1ccc(-c2ccc3c(=O)[nH]cnc3c2)cc1)Nc1ccc(F)c(F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50650863   

TargetVascular endothelial growth factor receptor 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of human VEGFR-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 99nMAssay Description:Inhibition of EGFR (unknown origin) using TK as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 142nMAssay Description:Inhibition of human c-Kit using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 176nMAssay Description:Inhibition of FGFR1 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 192nMAssay Description:Inhibition of human VEGFR-1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 500nMAssay Description:Inhibition of B-Raf (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 500nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEphrin type-B receptor 4(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of human EPHB4 by discoverX kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 8.87E+3nMAssay Description:Inhibition of TIE-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50650863(CHEMBL5632719)
Affinity DataIC50: 9.85E+4nMAssay Description:Inhibition of human recombinant PDGFRbeta using poly (Glu, Tyr)4:1 as substrate measured after 60 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed