BDBM50652114 CHEMBL5639882

SMILES COc1nc(F)ccc1CNc1ccc(Cc2c[nH]c3ncc(C)cc23)c(F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50652114   

TargetAurora kinase C(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50652114(CHEMBL5639882)
Affinity DataIC50: 16nMAssay Description:Inhibition of human AURKC by discoverX kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50652114(CHEMBL5639882)
Affinity DataIC50: 390nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50652114(CHEMBL5639882)
Affinity DataIC50: 860nMAssay Description:Inhibition of KIT (unknown origin) using ATP as substrate incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase C(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50652114(CHEMBL5639882)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of AURKC (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50652114(CHEMBL5639882)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed