BDBM50652490 CHEMBL5639303

SMILES COc1ccc(-c2ccnc3c(-c4noc(C)n4)c(C)nn23)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50652490   

TargetActivin receptor type-1(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant GST-tagged-ALK2 (147 to 509 residues) using Casein as substrate in presence of ATP by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant N-terminal GST tagged-c-KIT (544 to end residues) expressed in baculovirus infected Sf9 cells using Poly (Glu,Tyr) 4:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCasein kinase II subunit alpha(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant full-length C-terminal His tagged-CK2 alpha expressed in Escherichia coli using tetra-methylbenzidine as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant GST tagged-EGFR using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 156nMAssay Description:Inhibition of human recombinant CHK1 using CHKtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 334nMAssay Description:Inhibition of human recombinant TrkA using Poly (Glu,Tyr) 4:1 as substrate in presence of ATP by kinase-Glo luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant full-length PIM1 expressed in baculovirus infected Sf9 cells using S6K as substrate in presence of ATP by ADP-Glo lum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 537nMAssay Description:Inhibition of human recombinant GST tagged-RET using IRF-1Rtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 710nMAssay Description:Inhibition of human CDK2 by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Sana'a University

Curated by ChEMBL
LigandPNGBDBM50652490(CHEMBL5639303)
Affinity DataIC50: 759nMAssay Description:Inhibition of human recombinant GST tagged-ROS1 using IRF-1Rtide as substrate in presence of ATP by ADP-Glo luminescence kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed