BDBM50666461 CHEMBL6163488

SMILES C=CC(=O)Nc1ccc(NC(=O)c2ccc(C)c(C#Cc3cnc4cccnn34)c2)cc1

InChI Key InChIKey=PTOHLBJGKPJPOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666461   

TargetMast/stem cell growth factor receptor Kit(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666461BDBM50666461(CHEMBL6163488)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of wild type His-tagged KIT (unknown origin) extracted from Escherichia coli BL21 (DE3) by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666461BDBM50666461(CHEMBL6163488)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of wild type PDGFRA (unknown origin) extracted from Sf9 cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed