BDBM510886 2-cyclopropyl-4- {[(aR)-6-[6-(6- fluoropyridin-3-yl)- 3-(trifluoromethyl) imidazo[1,5-a]pyridine- 1-amido]spiro[3.3] heptan-2-yl]oxy}-1,3- thiazole-5- carboxamide::US11078197, Example 63::US11673886, Example 63
SMILES NC(=O)c1sc(nc1O[C@H]1C[C@@]2(C[C@@H](C2)NC(=O)c2nc(n3cc(ccc23)-c2ccc(F)nc2)C(F)(F)F)C1)C1CC1
InChI Key InChIKey=GAZSECRIOVRHBD-FXUCQVAHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 510886
Affinity DataIC50: 6.10nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair