BDBM525281 US11173137, Compound AK3-101A::US11173137, Compound AK3-99B::US11173137, Compound FA44

SMILES [O-]C(=O)c1ccccc1Nc1c(Cl)ccc(OCc2ccccc2)c1Cl

InChI Key InChIKey=OZERPKICLJNSGP-UHFFFAOYSA-M

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 525281   

TargetChloride channel protein 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataIC50: 2nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetChloride channel protein 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataIC50: 620nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetChloride channel protein 2(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataIC50: 2.98E+3nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataKi:  3.00E+3nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataKi:  5.00E+3nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M5(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 1(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent

TargetChloride intracellular channel protein 1(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound FA44 | US11173137, Compound A...)
Affinity DataIC50: 1.00E+8nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
US Patent