BDBM525281 US11173137, Compound AK3-101A::US11173137, Compound AK3-99B::US11173137, Compound FA44

SMILES [O-]C(=O)c1ccccc1Nc1c(Cl)ccc(OCc2ccccc2)c1Cl

InChI Key InChIKey=OZERPKICLJNSGP-UHFFFAOYSA-M

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 525281   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataKi:  3.00E+3nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataKi:  5.00E+3nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataKi: >1.00E+4nMAssay Description:Two exemplary compounds, FA44 and FA26, were screened against a panel of CNS receptors, transporters, and ion channels to examine specificity for CLC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChloride channel protein 2(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataIC50:  620nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChloride channel protein 2(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataIC50:  2.98E+3nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChloride intracellular channel protein 1(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataIC50: >1.00E+8nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetChloride channel protein 2(Human)
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM525281(US11173137, Compound AK3-101A | US11173137, Compou...)
Affinity DataIC50:  2nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent