BDBM551188 3-(7-(Prop-1-en-2-yl)-1H-indazol-5-yl)-2,5-bis(trifluoromethyl)-3H-imidazo[4,5-::US11312712, Example 305

SMILES C=C(C)c1cc(-n2c(C(F)(F)F)nc3ccc(C(F)(F)F)nc32)cc2cn[nH]c12

InChI Key InChIKey=GSWWUHFZVOIDOJ-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551188   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 551188BDBM551188(3-(7-(Prop-1-en-2-yl)-1H-indazol-5-yl)-2,5-bis(tri...)
Affinity DataIC50: 0.0200nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
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Date in BDB:
8/6/2022
Entry Details
US Patent