BDBM551188 3-(7-(Prop-1-en-2-yl)-1H-indazol-5-yl)-2,5-bis(trifluoromethyl)-3H-imidazo[4,5-::US11312712, Example 305

SMILES CC(=C)c1cc(cc2cn[nH]c12)-n1c(nc2ccc(nc12)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=GSWWUHFZVOIDOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551188   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM551188(3-(7-(Prop-1-en-2-yl)-1H-indazol-5-yl)-2,5-bis(tri...)
Affinity DataIC50:  0.0200nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent