BDBM560834 2-(4-(6-fluoroquinolin-4-yl)-1-hydroxycyclohexyl)-N-(4-(pentafluoro-lambda6-sulfanyl)phenyl)acetamide::US11389445, Compound 5

SMILES OC1(CC(=O)Nc2ccc(cc2)S(F)(F)(F)(F)F)CCC(CC1)c1ccnc2ccc(F)cc12

InChI Key InChIKey=PQPFEZORLKFHLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560834   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM560834(US11389445, Compound 5 | 2-(4-(6-fluoroquinolin-4-...)
Affinity DataIC50: 50nMAssay Description:The experimental principle is summarized as follows: IDO expression is low in Hela cells under no induction, but a certain concentration of IFN-γ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent