BDBM578329 US11478474, Compound 177::US12070457, Compound 177

SMILES COCCN1CCn2nc(Nc3cc(cn(C)c3=O)-c3ccnc(c3CO)-n3ccn4c5ccccc5c(F)c4c3=O)cc2C1

InChI Key InChIKey=LGIHQRSRDQBYSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578329   

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578329(US11478474, Compound 177 | US12070457, Compound 17...)
Affinity DataIC50: 6nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578329(US11478474, Compound 177 | US12070457, Compound 17...)
Affinity DataIC50: 6nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent