BDBM578353 US11478474, Compound 201::US12070457, Compound 201

SMILES C[C@@H]1CN([C@@H](C)CN1C1COC1)c1ccc(Nc2cc(nn(C)c2=O)-c2ccnc(c2CO)-n2ccn3c4CC(C)(C)Cc4cc3c2=O)nc1

InChI Key InChIKey=NAIFWZQZJRAGQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 578353   

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578353(US11478474, Compound 201 | US12070457, Compound 20...)
Affinity DataIC50: 5nMAssay Description:Z′-LYTE biochemical assay employs a fluorescence resonance energy transfer (FRET)based, coupled-enzyme format and is based on the differential ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578353(US11478474, Compound 201 | US12070457, Compound 20...)
Affinity DataIC50: 5nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM578353(US11478474, Compound 201 | US12070457, Compound 20...)
Affinity DataIC50: 9nMAssay Description:The experiment were carried out according to the instructions of the Z′-LYTE kinase test kit-tyrosine 1 peptide. Reagent preparation: 1.33�� ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2024
Entry Details
US Patent