BDBM606262 US11685719, Example 28A::US11685719, Example 28B
SMILES Cc1cnc(COc2cc(C)n(-c3cc(ncc3C)-n3ccnc(c3=O)C(C)(C)O)c(=O)c2Cl)c(F)c1
InChI Key InChIKey=MKHGLLWUWDYQIR-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 606262
Affinity DataIC50: 1nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14/MAP kinase-activated protein kinase 5(Human)
Xinthera
US Patent
Xinthera
US Patent
Affinity DataIC50: >3.16E+5nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
Affinity DataIC50: >100nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14/MAP kinase-activated protein kinase 5(Human)
Xinthera
US Patent
Xinthera
US Patent
Affinity DataIC50: 3.16E+3nMAssay Description:A typical assay was conducted in 20 μL volume including 60 μM active p38α (Carna, cat #04-152), 10 μM ATP, 1 μM FITC-HSP27 p...More data for this Ligand-Target Pair