BDBM611723 US11718609, Compound BT2184

SMILES COc1cc2nc(nc(NCCNS(=O)(=O)c3ccccc3)c2cc1OC)-c1cccc2cccnc12

InChI Key InChIKey=SFXWXNMUDJAZQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 611723   

TargetHeparanase(Human)
Beta Therapeutics

US Patent
LigandPNGBDBM611723(US11718609, Compound BT2184)
Affinity DataIC50: 3.39E+3nMAssay Description:Recombinant human active heparanase derived from Chinese hamster ovary cells was from R&D Systems. Bovine serum albumin-coated 96 well microplates (9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

TargetHeparanase(Human)
Beta Therapeutics

US Patent
LigandPNGBDBM611723(US11718609, Compound BT2184)
Affinity DataIC50: 3.39E+3nMAssay Description:Recombinant human active heparanase derived from Chinese hamster ovary cells was from R&D Systems. Bovine serum albumin-coated 96 well microplates (9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent