BDBM611726 US11718609, Compound BT2229

SMILES COc1cc2nc(NCCNC(=O)c3nnc(s3)-c3ccccc3)nc(N)c2cc1OC

InChI Key InChIKey=NXRRIKJWDOCPRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 611726   

TargetHeparanase(Human)
Beta Therapeutics

US Patent
LigandPNGBDBM611726(US11718609, Compound BT2229)
Affinity DataIC50: 1.34E+4nMAssay Description:Recombinant human active heparanase derived from Chinese hamster ovary cells was from R&D Systems. Bovine serum albumin-coated 96 well microplates (9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

TargetHeparanase(Human)
Beta Therapeutics

US Patent
LigandPNGBDBM611726(US11718609, Compound BT2229)
Affinity DataIC50: 1.34E+4nMAssay Description:Recombinant human active heparanase derived from Chinese hamster ovary cells was from R&D Systems. Bovine serum albumin-coated 96 well microplates (9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent