BDBM615786 US20230271954, Compound 85::trans-6-chloro-4-4-((cyclopropylmethyl)(3,4- difluoro-5-methoxyphenyl)amino)cyclohexyl) (methyl)amino)-1-methyl-2-oxo-1,2-dihydro-1,5- naphthyridine-3-carbonitrile

SMILES COc1cc(cc(F)c1F)N(CC1CC1)C1CC[C@@H](CC1)N(C)c1c(C#N)c(=O)n(C)c2ccc(Cl)nc12

InChI Key InChIKey=XHXXIBIHMVISQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615786   

TargetDiacylglycerol kinase zeta(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615786(trans-6-chloro-4-4-((cyclopropylmethyl)(3,4- diflu...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615786(trans-6-chloro-4-4-((cyclopropylmethyl)(3,4- diflu...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent