BDBM620943 (4S)-4-methyl-3-(2-{[1-(2,2,2- trifluoroethyl)-1H-pyrazol-4- yl]amino}quinazolin-7-yl)-1,3- oxazolidin-2-one::US20230303540, Example Ex-7.21

SMILES C[C@H]1COC(=O)N1c1ccc2cnc(Nc3cnn(CC(F)(F)F)c3)nc2c1

InChI Key InChIKey=HQBIYRLFYFTPCZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620943   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM620943(US20230303540, Example Ex-7.21 | (4S)-4-methyl-3-(...)
Affinity DataIC50: 0.625nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent