BDBM620943 (4S)-4-methyl-3-(2-{[1-(2,2,2- trifluoroethyl)-1H-pyrazol-4- yl]amino}quinazolin-7-yl)-1,3- oxazolidin-2-one::US20230303540, Example Ex-7.21
SMILES C[C@H]1COC(=O)N1c1ccc2cnc(Nc3cnn(CC(F)(F)F)c3)nc2c1
InChI Key InChIKey=HQBIYRLFYFTPCZ-JTQLQIEISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 620943
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 0.625nMAssay Description:The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen technology from Life Technologies Corporation (Carlsbad, CA...More data for this Ligand-Target Pair