BDBM621064 US20230303562, Example 2::US20230303562, Example 3

SMILES Cc1cccc(n1)-n1nccc1-c1ccn2ncnc2c1

InChI Key InChIKey=WMPWZJBOZZHDFK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 621064   

TargetActivin receptor type-1(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621064(US20230303562, Example 3 | US20230303562, Example ...)
Affinity DataIC50: 9.83nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent

TargetActivin receptor type-1(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621064(US20230303562, Example 3 | US20230303562, Example ...)
Affinity DataIC50: 43.8nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent

TargetTGF-beta receptor type-2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621064(US20230303562, Example 3 | US20230303562, Example ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental method: According to the instructions of ADP-Glo Kinase Detection Kit (Promega), the inhibitory effect of the compounds of the present i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent

TargetTGF-beta receptor type-2(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM621064(US20230303562, Example 3 | US20230303562, Example ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Experimental method: According to the instructions of ADP-Glo Kinase Detection Kit (Promega), the inhibitory effect of the compounds of the present i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2023
Entry Details
US Patent